Recently Asked HR Pharmacy Interview Questions
Q – 1 In Dry powder inhalation Andersen casacde impacor for FPF performing in that we adjusting 60LPM/MIN and time 4second, why? Explain?
Ans- As per USP guideline the normal healthy person is having Lungs Air volume Capacity is 4lit. and when we measure the air flow at that litre,so flow metre will show the air flow 60. thus it mean 1 second per 1 Litre, so for the 4 litre is required 4 second , that’s why we performed the Andeson Cascade at 60LPM/MIN and at 4 second
Q – 2 What is the Ph of blood?
Ans- The normal pH of blood running through arteries that carry blood from the heart to other parts of the body) is 7.4; the pH of blood in the veins (vessels that transports blood to the heart) is about 7.35
Q – 3 What is streptococcus and what is the best drug for it?
Ans- Spherical Gram-positive bacteria occurring in pairs or chains; cause e.g. scarlet fever and tonsillitis drugs; penicillin, amoxilin, cephlosporins.
Q – 4 What the procedure followed in pharmacokinetic study of drug in plasma?
Ans- Pharmacokinetic studies of a drug in plasma were conducted by noncompartmental analysis,compartmental analysis,bioanalytical method and by mass spectroscopy.
Q – 5 What will be in case stability sample Which have batch but distribute in three country. In tath case< we can put the sample for all country, whenevr all have same temp(Zone)?
Ans- Stability of sample doesnot depend on material you had sent in different coutries.you should carry long term stablility of only one retained sample as per ICH guidelines (temp and humidity conditions).
Q – 6 What is eCTD? Difference between CTD & eCTD? How it will be prepared? Need of any Software?
Ans- The guidance on marketing applications for drugs and biologics, known as the Common Technical Document (CTD), was finalized by the International Conference on Harmonization (ICH) in 2003. Today the CTD format is mandatory for paper-based marketing applications in Europe, Japan, Canada, and other regions, and is highly recommended by FDA.
The eCTD format has become mandatory in key regions for electronic submissions. Since January 2010, the European Medicines Agency has required all applications in the centralized procedure use the eCTD format. Since January 2008 FDA CDER has required all electronic submissions be in the eCTD format. FDA CBER requires the eCTD format for priority review and rolling submissions.
Q – 7 What is the definition of Pka?
Ans- It is an equilibrium constant, Used for the dissociation of a weak acid. it is also known as acid ionisation constant
Q – 8 What is the major definition and difference between uniformity of content and content uniformity as official test for all tablets?
Ans- uniformity of content(dosage unit):is by two method by weight variation and by content uniformity.wt variation means performing assay annd relating with indiviual unit weight of dosage form.and content uniformity means for ten sample (dosage unit) individually analysed
Q – 9 Explain difference b/w sonication and homozinization?
Ans- Homogenization is intensive blending of mutually related substances or groups of mutually related substances to form
a constant of different insoluble phases (sometimes with addition of surfactants) to obtain a suspension or emulsion.
Sonication is the act of applying sound (usually ultrasound) energy to agitate particles in a sample, for various purposes.
Q – 10 DEFINITION OF STABILITY INDICATING METHOD?
Ans- in stability indicating we do the stress testing by applying different condition so that it can be suitable for stability testing in stability study till completion
Q – 11 ONLINE TRAINING IN ORACLE CLINICAL 4.6 (Clinical Data Management) and SAS -SDTM mapping?
Ans- KARMEL Biosciences is an international reputed Clinical Services Organization providing full range of Clinical Data Management services to global pharma and biotech Companies.Karmel Bio has concluded agreements with multiple major hospitals in India and China for ICH- GCP Training of Investigators and site Monitors. Karmel Bio also conducts the international conferences and seminars in India and China.
We are offering online training in Clinical Data Management and Advanced Clinical SAS
1)Oracle Clinical 4.6 (Clinical Data management) 2)Advanced Clinical SAS (SDTM mapping) 3)Live project in Clinical Data Management
Q – 12 Explain what are the role of MR?
Ans- MR means medical representative.,Medical rep has to sell products of pharma companies or drug manufacturers. He has to go to doctors and medical shops to sell drugs and promote drugs. He will ask physicians to refer his drugs for the patient. He will give some free samples etc.