Latest Biotechnology Interview Questions Part – 4
How Many Types Of Histamine Receptors Are There And What Are They?
There are three types of histamine receptors. They are H1, H2 and H3.They has different tissue distributions.
What Is The Reaction-taking Place When H2 Receptor Binds To Mast Cells And Basophils?
When H2 binds to mast cells and basophils it suppresses degranulation.
Explain In Brief About Leukotrienes And Prostaglandins?
Leukotrienes and prostaglandins are formed only when the mast cell undergo degranulation and enzymatic break down of phospholipids in the plasma membrane.
The effects produced by them are more pronounced and long lasting than histamine. Leukotrienes mediate mucous production and bronchoconstriction. Prostaglandin D2 causes bronchoconstriction.
Explain In Brief About Cytokines?
Cytokines activate inflammatory cells such as neutrophils and eosnophils.IL-5 is important in activation of eosnophils, IL-4 increases IgE production by B-cells. IL-4, Il-5, IL-6, TNF-a has been secreted by human mast cells.
What Is Atopic Dermatitis?
Atopic dermatitis is an inflammatory skin disease. This disease is observed frequently in young children. There will be skin eruptions.
What Is Erythroblastosis Fetalis?
It is a hemolytic disease, which develops in newborn. Maternal IgG antibodies cross the placenta and destroy the red bleed cells. This develops when an Rh+ expresses an Rh antigen on blood cells that the mother does not express.
What Is A Rhogam?
Is an antibody that binds to any of the blood cells, enter the mother’s blood circulation, and facilitate their clearance by activation of B-cells and memory cell production.
What Is Type Iii Hypersensitivity?
It is immune complex mediated hypersensitivity. Typical manifestations include rheumatoid arthritis, serum sickness, necrotizing etc.
Name Some Infectious Diseases?
Some of the Infectious diseases are Malaria, meningitis, trypanosomiasis, hepatitis etc…
Name Some Autoimmune Diseases?
Rheumatoid arthritis, systemic lupus erythematosus, good pasture’s syndrome
How Many Types Of Hypersensitive Reactions Are There?
There are four types of hypersensitive reactions, they are:
Type I hypersensitive reaction
Type II hypersensitive reaction
Type III hypersensitive reaction
Type IV hypersensitive reaction
What Are The Steps In Bacterial Infection?
There are four steps in bacterial infection. They are:
Attachment to host
Proliferation
Invasion of host tissue
Toxin-induced damage to host cell
What Is The Disease Caused By Rotavirus?
The disease caused by rotavirus is infantile diarrhea.
What Is The Disease Caused By Sabia Virus?
Brazilian haemorrhagic
What Is The Disease Caused By Ebola Virus?
Ebola haemorrhagic fever
What Is The Disease Caused By Hepatitis C?
Non-A, Non-B hepatitis are commonly transmitted via transfusion.
What Is The Disease Caused By Toxin Producing Strains Of Staphylococcus Aureus?
Toxic shock syndrome
What Is Atopy?
The tendency to manifest localized anaphylactic reactions is called atopy.
What Would An Inhalation, Ingestion Exposure As Well As To The Eyes Of Butane, Diethylene Glycol Monobutyl Ether, Monoethanolamine (mea), & Sodium Hydroxide Do To The Human Body?
Sodium hydroxide is a very caustic substance – severe burns on skin contact, can cause severe eye irritation and burning – can severely damage surface of eye causing blindness (permanent), severe burring on ingestion and inhalation.
Butane is a gas – it is very toxic if inhaled – acts like an anesthetic – can stop person breathing very quickly.
Diethyleneglycol monobutyl ether is less acutely toxic but does have long-term toxicity on various organs.
What Are Low Affinity Receptors?
Low affinity receptors play role in regulating he intensity of IgE response.